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Project Title: Development of new diagnostic assays and epidemiological surveillance of viral pathogens of livestock in Africa

Donor: Centro de Investigacion en Sanidad Animal (CISA- INIA), Spain
Partner/Institution: Department of Veterinary Services, Kenya, National Veterinary Research Centre, Kenya, Sokoine University of Agriculture, Tanzania
Project Highlight: Sensitive and specific diagnostic tests to discriminate livestock pathogens are essential for disease surveillance and to support cost effective and targeted deployment of control measures. Such diagnostic tools enable collection of data for input to impact assessment and modelling of health constraints to livestock production and both regional and International trade. The project seeks to build on the initial successful collaboration between CISA- INIA and ILRI on three viral diseases, African Swine Fever (ASF), Rift valley Fever ( RVF) and Lumpy skin disease (LSD) that are important in constraining trade in Africa. The major focus will remain (ASF) (for which CISA-INIA is an OIE and EU reference centre). This is due both to the growing importance of the swine sector in sub-Saharan Africa and the threat posed regionally and globally to trade in pigs and pig products. There will be additional work on Rift Valley Fever (RVF) and LSD.
In phase 1 of the project, the expertise of CISA has been appplied to initiating development of improved antigen-specific serological tests for ASF use in East Africa, determining viral prevalence in the region and analysing molecular epidemiology using nucleic acid based methods. An experimental ELISA antibody detection ELISA has been developed for RVF detection. It is planned that work will also begin on LSD in 2007-2008.
In phase 2 the project will build on the initial work to develop improved diagnostic assays for use in Africa and put increased emphasis on technology transfer and capacity building within the region.
Total Project Budget $US: 600,000.00
Scientist Involved: Richard Bishop
Scientist Email: Email: r.bishop@cgiar.org

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