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Appolinaire Djikeng

Email: a.djikeng@cgiar.org, adjikeng@gmail.com

Technology Manager ,Biosciences eastern and central Africa(BecA)-ILRI Hub

Dr. Appolinaire Djikeng is the Technology Manager at the Biosciences eastern and central Africa (BecA) Hub and leads various teams focusing on 1) the acquisition and management of laboratories technologies, 2) provision of research related services and overall laboratory management, and 3) research activities in the areas of genomics and metagenomics.

Prior to joining the BecA-ILRI Hub, Dr. Djikeng was an Assistant Professor at the J Craig Venter Institute in the United States. Dr. Djikeng received his B.Sc.(Hons) and M.Sc. from the University of Yaoundé I in Cameroon, and he graduated with a PhD from Brunel University in London, England. He conducted his postdoctoral research work at Yale University School of Medicine in the USA. In addition to his work at BecA, Dr. Djikeng currently teaches various courses at selected universities in Sub-Saharan Africa, specifically Ethiopia and Cameroon.

Curriculum Vitae

Name: Dr. Appolinaire Djikeng

Country of birth: Cameroon

Nationality:  Cameroonian

Position Title: Technology Manager

Institution: Biosciences eastern and central Africa(BecA)-ILRI Hub

Contact Address:

BecA Hub ILRI PO Box 30709 Old Naivasha Road Nairobi, Kenya 00100

Email: a.djikeng@cgiar.org, adjikeng@gmail.com

Tel: -

Specialty Area:

Education:

1991  B.Sc., University of Yaounde I, Cameroon

1994  M.Sc., M.Phil., University of Yaounde I, Cameroon

1999  Ph.D., Brunel University, England

Positions held (since terminal degree):

2007 - 2009   Assistant Professor, The J Craig Venter Institute, USA

2004 - 2007   Staff Scientist, Parasite Genomics, The Institute for Genomic Research (TIGR), USA

2003 - 2004  Associate Research Scientist (Research Faculty Position), Dept of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, USA

1999 - 2003  Postdoctoral Associate, Dept of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, USA

Expertise:

Honors and Awards (since terminal degree):

2003  Award for the Best Oral presentation at the 14th Molecular Parasitology Meeting (MPM), Woods Hole, Massachusetts, USA. .

2003  Award of the American Society of Tropical Medicine and Hygiene for Scientific Excellence in Molecular, Cellular and Immunoparasitology .

2001   A. Brown Coxe Post-doctoral Fellowship .

A selection of major research accomplishments: Discoveries and first reports

A Selection of refereed journal publications (2002-present)

Simoes MC, Lee J, Djikeng A, Cerqueira GC, Zerlotini A, da Silva-Pereira RA, Dalby AR, Loverde P, El-Sayed NM, Oliveira G., Identification of Schistosoma mansoni microRNAs. BMC Genomics. 2011. [Epub ahead of print] PMID: 21247453.

Ouwe Missi Oukem-Boyer, O., Djikeng, A. 2010. Tackling HIV/AIDS: Developing a health information library network in Cameroon. Elsevier Library Connect Newsletter. 8:8 (November 2010).

Djikeng, A., Kuzmickas, Anderson, N., Spiro, D. 2009. Viral metagenomics of Lake Needwood. PlosONE 4: e7264.

Guerrero, F. D., Dowd, S. E., Djikeng, A., Wiley, G., Macmil, S., Saldivar, L., Najar, F. and Roe, B.A. 2009. A Database of Expressed Genes from the New World Screwworm, Cochliomyia hominivorax (Coquerel) (Diptera: Calliphoridae). Journal of Medical Entomology. 46: 1109-16.

Berriman, M., Ghedin, E. Djikeng, A. Melville, S., and El-Sayed, N. M. 2005. The genome of the African trypanosome Trypanosoma brucei. Science. 359: 416-422.

Chamond, N., Shi, H., Djikeng, A., Tschudi, C. and Ullu, E. 2009. RNA interference in Trypanosoma brucei: on the role of the amino terminal RGG domain and the polyribosome association of Argonaute 1. Journal of Biological Chemistry. 284:36511-20.

Djikeng, A., Spiro, D 2009. Advancing full lenght genome sequencing of human viral pathogens. Future virology. 4: 47-53.

Palmenberg, A., Spiro, D., Kuzmickas, R. Wang, H., Djikeng, A., Rathe, J. A., Fraser-Liggett, C.M. and Liggett, S.B. 2009. Phylogenetic analyses of human rhinoviruses reveal viral structure and evolution. Science. 324: 55-9.

Bartholomeu, D., Cerqueira, G., Leao, A.C., DaRocha, W., Pais, F., Macedo, C., Djikeng, A., Teixeira, S., El-Sayed, N. 2009. Genomic organization and expression profile of the Mucin-Associated Surface Protein (masp) family of the human pathogen Trypanosoma cruzi. Nucleic Acids Res. 37: 3407-17.

Djikeng, A., Raverdy, S., Foster, J., Bartholomeu, D., Zhang, El-Sayed, N.M. and Carlow, C. 2007. Cofactor-independent Phosphoglycerate Mutase is an essential gene in procyclic form Trypanosoma brucei. Parasitology Research. 100: 887-92.

Djikeng, A., Halpin, R, Kuzmickas, R, Sengamalay, N, Alfonso, C, Xang, X, Anderson, NG, Ghedin, E, Spiro, DJ. 2007. Viral genome sequencing by random priming methods BMC Genomics. 9:5.

Berriman, M., Haas, B., ... Djikeng, A., ... Barell, BG., and El-Sayed , NM. 2009. The genome of the blood fluke Schistosoma mansoni. Nature. 460: 352-358.

El-Sayed, N. M., Myler, P. ... Djikeng, A. ... Stuart, K., and Hall, N. 2005. Comparative genomics of trypanosomatid parasitic protozoa. Science. 359: 404-409.

Shi, H*., Djikeng, A*., Chamond, N., Ngo, H., Tschudi, C and Ullu, E. 2005. Repression of gene expression by the coliphage MS2 coat protein in Trypanosoma brucei. Mol Biochem Parasitol. 144: 119-122. (Joint first authorship)

Djikeng, A., Shen, S., Tschudi, C., and Ullu, E. 2004. Analysis of gene function in Trypanosoma brucei Using RNA Interference. Methods Mol Biol. 265: 73-84.

Shi, H., Djikeng, A., Tschudi, C. and Ullu, E. 2004. An Argonaute protein in the early divergent eukaryote Trypanosoma brucei: control of siRNA accumulation and retroposon transcript. Molecular and Cellular Biology. 24: 420-427.

Djikeng, A., Shi, H., Tschudi, C., Shen, S., and Ullu, E. 2003. An siRNA ribonucleoprotein is found associated with polyribosomes in Trypanosoma brucei. RNA. 9: 802-808.

Tschudi, C., Djikeng, A., Shi, H. and Ullu, E. 2003. In vivo analysis of the RNA interference mechanism in Trypanosoma brucei. Methods. 30: 304-312.

Book chapters:

Djikeng, A, Nelson, B. J., and Nelson, K. E. 2010. Implications of the human microbiome research for the developing world. In: Karen E. Nelson (ed.). Metagenomics of the Human Body. Springer.

Djikeng, A., Shen, S., Tschudi, C. and Ullu, E. 2004. Analysis of gene function in Trypanosoma brucei using RNA interference. In: Sara Melville (ed.). Parasite Genomics Protocols. The Humana Press Inc. pp. 287-298.

Invited presentations at major international conferences (2002-present-Maximum 8)

Djikeng, A. 2007. Genomics and Post-Genomics: the case of viruses and African trypanosomes. Conference of the Southern and Eastern Africa Network of Analytical Chemists (SEANAC). Gaborone, Botswana. July 2007.

Djikeng, A. 2007. Genomics and Emerging Viral Infectious Diseases. Bioinformatics for Africa (Conference on the Bioinformatics of African Pathogens and Disease Vectors). Nairobi, Kenya. May 2007.

Djikeng, A. 2006. Global Science Corps in Perspective. Strategic Planning Meeting of the Global Science Corps (GSC) initiative; hosted by the African Academy of Sciences. Nairobi, Kenya. January 2006.

Djikeng, A. 2003. Role of a T. brucei Argonaute protein in the RNAi pathway. 52nd Meeting of the American Society of Tropical Medicine and Hygiene: Symposium on Molecular, Cellular and Immunoparasitology. Philadelphia, PA, USA. December 2003.

Research Grants (2004 – present):

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This database is supported with funding from the Bill & Melinda Gates Foundation