Deprecated: mysql_connect(): The mysql extension is deprecated and will be removed in the future: use mysqli or PDO instead in /home/afribio/public_html/hub/scientists/library/database.php on line 4
Africa Scientist

 

Rachel Chikwamba

Email: rchikwamba@csir.co.za

Principal Scientist, Plant Biotechnology &Research Manager &Adjunct Senior Lecturer,Council for Scientific & Industrial Research (CSIR) University of Pretoria , South Africa


Deprecated: preg_replace(): The /e modifier is deprecated, use preg_replace_callback instead in /home/afribio/public_html/hub/scientists/scientist.php on line 18

Deprecated: preg_replace(): The /e modifier is deprecated, use preg_replace_callback instead in /home/afribio/public_html/hub/scientists/scientist.php on line 22

Deprecated: preg_replace(): The /e modifier is deprecated, use preg_replace_callback instead in /home/afribio/public_html/hub/scientists/scientist.php on line 23

Rachel Chikwamba is a principal scientist in the Plant Biotechnology group at the CSIR Biosciences.  In addition, she holds an adjunct position as a senior lecturer in the Department of Botany and the Forestry and Agricultural Research Institute (FABI), at the University of Pretoria, South Africa.

Dr. Chikwamba has worked in programs on the application of biotechnology in resource poor small scale agriculture and has participated in many regional initiatives on the development of policies and priorities on biosafety and agricultural biotechnology research in Southern Africa. Her interest in crop improvement research is the use of biotechnology tools to alleviate biotic and abiotic stresses in crop plants. 

She is currently involved in many collaborative research initiatives funded by the Royal Society, the EU Sixth Framework, the Bill & Melinda Gates Foundation and the Rockefeller Foundation.  Dr. Chikwamba is a Fellow of CSIR Biosciences, an Honorary Research Fellow at St Georges, University of London, and a member of the Academy of Science of South Africa.  Main research work under her leadership involves the improvement of grain nutritional quality primarily in sorghum but also in soybean.  This research is undertaken collaboratively in global consortia.

 

 

Curriculum Vitae

 

Name: Dr. Rachel Chikwamba

Country of birth:

Nationality:  

Position Title: Principal Scientist, Plant Biotechnology &Research Manager &Adjunct Senior Lecturer

Institution: Council for Scientific & Industrial Research (CSIR) University of Pretoria , South Africa

Contact Address:

-PO Box 395 Pretoria 0001

Email: rchikwamba@csir.co.za

Tel: -+27 (0) 12 841 2177

Fax: -+27 (0) 12 841 3651

Specialty Area:

 

Education:

1989  BSc (Agriculture Honours),University of Zimbabwe.

1992  MSc (Genetics and plant breeding), University of Queensland, Australia.

2002  PhD (Genetics), Iowa State University, USA.

 

Positions held (since terminal degree):

 

Expertise:

 

 

 

Honors and Awards (since terminal degree):

 

 

A selection of major research accomplishments: Discoveries and first reports

 

 

 

A Selection of refereed journal publications (2002-present)

 

R. Chikwamba, Sangtong, V, D.L. Moran, K. Wang, W. Woodman-Clikeman, M.J. Long, M. Lee, and M.P. Scott (2002). Expression and inheritance of the wheat Glu-1DX5 gene in transgenic maize. Theoretical and Applied Genetics, 105(6-7): 937-945.

 

Rachel Chikwamba, Jennifer McMurray, Bronwyn Frame, Paul Scott Hugh Mason, Kan Wang (2002). Expression of a Bacterial Antigen in Maize: The Role of Regulatory Sequences, Inheritance and Level of Expression of the Synthetic E. coli Heat Labile Toxin B Sub-unit (LT-B) in Maize. Molecular Breeding, 10: 253-263.

 

Rachel Chikwamba, Joan Cunnick, Diane Hathaway, Jennifer McMurray, Hugh Mason, Kan Wang (2002). A Functional Antigen in A Practical Crop: Maize Synthesized LT-B Protects Mice Against Escherichia coli Heat Labile Enterotoxin (LT) And Cholera Toxin (CT). Transgenic Research, 11: 479-493.

 

Rachel Chikwamba, Lorena Mejia, Paul Scott, Hugh Mason, Kan Wang (2003). Immunolocalization of bacterial LT-B in transgenic maize kernels. PNAS, 100 (19): 11127-32.

 

Rachel Chikwamba, Julian K-C Ma, Penny Sparrow, Rainer Fischer, Richard Mahoney and Richard M Twyman (2005). Plant Derived Pharmaceuticals - the road forward. Trends in Plant Sciences, 10 (12): 580 -585.

 

Chakauya, E; Chikwamba, R; Rybick, EP (2006). Riding the tide of biopharming in Africa: considerations for risk assessment. South African Journal of Science. , Vol. 102(7-8), pp 284-288

 

 

Book chapters:

Kan Wang, Rachel Chikwamba, Joan Cunnick (2003). Plant-based oral vaccines. In: Novel Vaccination Strategies for Infectious Diseases. Editor: Stefan H.E. Kaufmann pp 387-407.

Hugh S. Mason, Rachel Chikwamba, Luca Santi, Richard T. Mahoney and Charles J. Arntzen (2004) Transgenic Plants For Mucosal Vaccines, In Mucosal Immunology (3rd edition) (P.L. Ogra, J. Mestecky, M.E. Lamm, W. Strober, J. R. McGhee, J. Bienenstock, eds.), Academic Press, San Deigo, CA.

 

 

Invited presentations at major international conferences (2002-present-Maximum 8)

 

Chikwamba, R.K. (2004). Plant vaccines and issues in public health. Paper delivered at Plant-derived vaccines and antibodies: potential and limitations. Fondation Mérieux, Veyrier du Lac, near Annecy (French Alps). 21-24 March 2004

 

Rachel Chikwamba, Joan Cunnick, Diane Hathaway, Jennifer McMurray, Huixia Shou, Bronwyn Frame, Sue Ellen Pegg, Paul Scott, Hugh Mason, Kan Wang. Expression and Immunogenicity of a Synthetic E. coli Heat Labile Enterotoxin B Sub-unit (LT-B) as a Model Vaccine in Maize. Poster presented at the 10th IAPTC

 

Chikwamba, R.K., Mason, H.S., Mahoney, R., and Arntzen, C.J., (2004). Transgenic plants: A new biopharmaceutical manufacturing platform. Paper presented at the 8th International Symposium on the Biosafety of Genetically Modified Organisms. September 26-30, Montpellier, France.

 

T. Lotter, K. Ramessar, N. Dube and R. Chikwamba (2006). Expression of Rabies Chimeric MAb heavy chain (E559VH-4E10CH) and MAb light chain (E559VL-4E10CL) in Zea Mays. Paper presented at the Pharmaplanta consortium meeting, Aachen, Germany.

 

herese Lotter, Nosisa Dube, Koreen Ramesaar and Rachel Chikwamba (2006). Novel Platforms for Essential Biomolecules: Expression of Antibodies in Plants. Paper presented at the CSIR Research and Innovation Conference, February 24, 2006.

 

Chikwamba, R.K. (2006). Issues in Global Food Security. Paper Presented at Bio2Biz 2006. 27-29 September 2006. Durban, South Africa.

 

Research Grants (2004 – present):

Funding source

Grant Title (Principal investigators)

Amount US$

Period

 


Home

This database is supported with funding from the Bill & Melinda Gates Foundation