Gregory Martin

Email: gbm7@cornell.edu

Professor, Plant Pathology and Plant-Microbe Biology,Cornell University

Gregory Martin is a professor in the Department of Plant Pathology and Plant-Microbe Biology at Cornell University and a scientist at the Boyce Thompson Institute for Plant Research. His research over the past 20 years has focused on the molecular mechanisms that bacteria use to infect plants and the mechanisms used by plants to resist bacterial infection. The experimental system for this work has been the interaction between tomato and Pseudomonas syringae pv. Tomato (the causative agent of bacterial speck disease). Martin has supervised the research projects of over 40 undergraduate students, and has trained 13 graduate students and 29 postdoctoral associates. He currently teaches an undergraduate course on “Innate immunity in Plants, Flies, and Humans” and a graduate course on “Molecular Plant-Microbe Interactions”. Dr. Martin has been an investigator on several NSF-funded projects that were directed at either development of genomics resources for use in tomato improvement or at the exploitation of natural variation in both Pseudomonas syringae and tomato in order to understand the molecular basis of plant defense responses. His research is currently funded by NIH, NSF, USDA, and USDA-BARD.

Martin has traveled extensively to developing countries and he lived in Malawi from 1983 to 1984 where he conducted research at the Bunda College of Agriculture as part of a USAID Bean/Cowpea CRSP Project. He is interested in developing a project with scientists in sub-Saharan Africa that would be focused on biodiversity-based approaches to develop novel plant-based technologies for the control of bacterial diseases of plants.

Curriculum Vitae

 

Name: Prof. Gregory Martin

Country of birth: United States

Nationality:  

Position Title: Professor, Plant Pathology and Plant-Microbe Biology

Institution: Cornell University

Contact Address:

Department of Plant Pathology and Plant-Microbe Biology Cornell University Ithaca, NY 14853

Email: gbm7@cornell.edu

Tel: +607 254 1208

Fax: +607 255 6695

Specialty Area:

-          Molecular Plant Pathology

-          Plant Molecular Genetics

 

Education:

1979  B.Sc. - Michigan State University

1984  M.Sc. - Michigan State University

1989  Ph.D. - Michigan State University

 

Positions held (since terminal degree):

 

1989-1992  Postdoctoral Fellow, Cornell University

 

1992-1995  Assistant Professor, Department of Agronomy, Purdue University

 

1996-1998  Associate Professor, Department of Agronomy, Purdue University

 

1998-2004  Scientist, Boyce Thompson Institute for Plant Research

 

1998-Present  Professor, Department of Plant Pathology, Cornell University

 

2005-Present  Boyce Schulze Downey Chair, Boyce Thompson Institute for Plant Research

 

Expertise:

 

-          Application of plant molecular techniques

-          Genome sequencing & annotation

-          Host resistance

-          Molecular biology

-          Molecular diagnostics of plant disease

-          Molecular host-pathogen interactions on pathogens

-          Molecular Plant Pathology

-          Plant disease resistance breeding

-          Virology

 

 

Honors and Awards (since terminal degree):

 

1989  Postdoctoral Fellowship in Plant Biology, NSF .

1995  David and Lucile Packard Fellowship in Science and Engineering .

1997  Barry Chelm Memorial Lecturer, Michigan State University .

1997  Herbert Newby McCoy Award for Outstanding Research of the Year .

2000  Roger E. Koeppe Endowed Lecture .

2003  3rd Most Highly Cited Paper in the category of Plant and Animal Science .

2004  Most Highly Cited Author in category of Plant and Animal Science .

2004  Fellow of the American Association for the Advancement of Science .

2005  Boyce Schulze Downey Chair .

2005  Fellow of the American Academy of Microbiology .

2006  Grand Marnier Foundation Lecturer .

 

A selection of major research accomplishments: Discoveries and first reports

 

1)                  U.S. Patent No. 5,648,599: "Gene conferring disease resistance to plants by responding to an a virulence gene in plant pathogens". Inventors: Gregory B. Martin and Steven D. Tanksley. Issued July 15, 1997 to Cornell Research Foundation, Ithaca, NY.

2)                  U.S. Patent No. 6,653,533: "Activation of plant defense-related genes mediated by the physical interaction of serine/threonine protein kinases with transcription factors containing pathogenesis-related (PR) box binding domains". Inventors: Gregory B. Martin and Jian-Min Zhou. Issued November 25, 2003 to Purdue Research Foundation, West Lafayette, IN.

3)                  U.S. Patent No. 7,138,569: "Nucleic acids encoding Pseudomonas Hop proteins and use thereof". Inventors: Alan R. Collmer, James R. Alfano, Xiaoyan Tang, Robin C. Buell, and Gregory B. Martin. Issued November 21, 2006 to Cornell Research Foundation, Boyce Thompson Institute, Kansas State University, The Institute for Genomics Research, and the University of Nebraska.

 

 

A Selection of refereed journal publications (2002-present)

 

Chakravarthy, S., Velasquez, A.C., Ekengren, S.K., Collmer, A., and Martin, G.B. 2010. Identification of Nicotiana benthamiana genes involved in pathogen-associated molecular pattern-triggered immunity. Molecular Plant Microbe Interactions 23: 715-726

 

Ek-Ramos MJ, Avila J, Cheng C, Martin GB, Devarenne TP. 2010. The T-loop extension of the tomato protein kinase AvrPto-dependent Pto-interacting protein 3 (Adi3) directs nuclear localization for suppression of plant cell death. Journal of Biological Chemistry : [Epub ahead of print]

 

Kang HG, Oh CS, Sato M, Katagiri F, Glazebrook J, Takahashi H, Kachroo P, Martin GB, Klessig DF. 2010. Endosome-associated CRT1 functions early in resistance gene-mediated defense signaling in Arabidopsis and tobacco. Plant Cell 22: 918-36

 

Kelley BS, SJ, D'Amasceno CM, Chakravarthy S, Kim BD, Martin GB, Rose JK. 2010. A secreted effector protein (SNE1) from Phytophthora infestans is a broadly acting suppressor of programmed cell death. Plant Journal 62: 357-366

 

Nguyen HP, Yeam I, Angot A, Martin GB. 2010. Two virulence determinants of type III effector AvrPto are functionally conserved in diverse Pseudomonas syringae pathovars. New Phytologist : [Epub ahead of print]

 

Oh CS, Pedley KF, Martin GB. 2010. Tomato 14-3-3 protein 7 positively regulates immunity-associated programmed cell death by enhancing protein abundance and signaling ability of MAPKKKa. Plant Cell 22: 260-72

 

Yeam, I., Nguyen, H.P., and Martin, G.B. 2010. Phosphorylation of Pseudomonas syringae effector AvrPto is required for an FLS2/BAK1-independent virulence activity and recognition by tobacco. Plant Journal 61: 16-24

 

 

Book chapters:

 

 

Invited presentations at major international conferences (2002-present-Maximum 8)

 

Tel Aviv University, Department of Plant Sciences. Tel Aviv, Israel. February 13, 2007

 

Weizmann Institute, Rehovot, Israel. February 15, 2007

 

Symposium on Plant Innate Immunity. Meiji University, Tokyo, Japan. March 12-13, 2007

 

RIKEN Yokohama Institute, Plant Sciences Center. Yokohama, Japan. March 14, 2007

 

Nagoya University, Department of Biological Sciences. Nagoya, Japan. March 15, 2007

 

Nara Institute of Science and Technology. Nara, Japan. March 16, 2007

 

University of Geneva, Department of Plant Biology, Geneva, Switzerland. May 8, 2007

 

University of Lausanne, Department of Plant Molecular Biology, Lausanne, Switzerland. May 9, 2007

 

Research Grants (2004 – present):

Funding source

Grant Title (Principal investigators)

Amount US$

Period

BARD

Role of GRAS transcription factors in tomato disease resistance and basal defense

Present

NIH-NIGMS

Role of bacterial virulence proteins in plant cell death

Present

NSF

Exploiting tomato genomics resources to investigate basal plant defenses against pathogens

Present

NSF

Acquisition of a fluorescence stereoscope and laser scanning confocal microscope for spectral imaging of plant cells

Present

NSF-IBN

Role of MAPKKKa-mediated cell death in plant disease resistance and susceptibility

Present

USDA-NRI

Molecular characterization of two tomato protein kinases that promote disease susceptibility

Present

USDA-NRI

Role of an AvrPto-dependent Pto-interacting protein, Adi3, in the host response to Pseudomonas syringae

Present

USDA-NRI

Training Ph.D. scientists to decipher the genomes of plant pathogenic microbes

Present

 


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This database is supported with funding from the Bill & Melinda Gates Foundation